[HTML][HTML] Calcium-sensing receptor genotype and response to cinacalcet in patients undergoing hemodialysis

SM Moe, L Wetherill, BS Decker, D Lai… - Clinical Journal of the …, 2017 - ncbi.nlm.nih.gov
… polymorphisms of the CASR gene in patients receiving dialysis, with nearly half of …
responsiveness to cinacalcet was on the basis of the allosteric activation of the receptor by cinacalcet

The calcium-sensing receptor gene polymorphism rs1801725 and calcium-related phenotypes in hemodialysis patients

AE Grzegorzewska, D Bednarski… - Kidney and Blood …, 2018 - karger.com
cinacalcet [7-9], seem to be associated with calcium-sensingPatients stratified by CASR
rs1801725 genotypes and analyzed … to Cinacalcet in Patients Undergoing Hemodialysis. Clin J …

Calcium-sensing receptor gene polymorphism Arg990Gly and its possible effect on response to cinacalcet HCl

HM Rothe, WB Shapiro, WY Sun… - Pharmacogenetics and …, 2005 - journals.lww.com
responses to cinacalcet. We report data on seven end-stage renal failure patients who
were treated with regular haemodialysisgenotypic/phenotypic characteristics of calcium-sensing

[HTML][HTML] The impact of CASR A990G polymorphism in response to cinacalcet treatment in hemodialysis patients with secondary hyperparathyroidism

J Ngamkam, S Vadcharavivad, N Areepium… - Scientific Reports, 2021 - nature.com
calcium sensing receptor (CASR) A990G genetic polymorphism on parathyroid hormone
(PTH) lowering response to cinacalcet … between the two groups of genotypes in this study. Of G …

Calcium-sensing receptor gene polymorphisms and their effect on response to cinacalcet treatment in patients with secondary hyperparathyroidism in chronic kidney …

L Egshatyan, T Filippova, S Nuralieva… - Endocrine …, 2020 - endocrine-abstracts.org
… were enrolled 25 patients undego chronic hemodialysis with … In 3 months cinacalcet treatment
patients homozygous and … to the patients without this polymorphism in the genotype. The …

Pharmacogenetic analysis of cinacalcet response in secondary hyperparathyroidism patients

S Jeong, IW Kim, KH Oh, N Han, KW Joo… - Drug Design …, 2016 - Taylor & Francis
… which increases the sensitivity of the calcium-sensing receptor … In this study, the genotype
frequencies of the SNPs related to … events in SHPT patients undergoing dialysis. Therefore, the …

[HTML][HTML] Associations of the calcium-sensing receptor gene CASR rs7652589 SNP with nephrolithiasis and secondary hyperparathyroidism in haemodialysis patients

AE Grzegorzewska, M Paciorkowski, A Mostowska… - Scientific Reports, 2016 - nature.com
… and the response to treatment with the calcimimetic agent cinacalcet … influences the response
to calcimimetics in patients with … doses of cinacalcet were similar in the genotype-stratified …

… role of vitamin D-binding protein and vitamin D receptor polymorphisms in the treatment response of dialysis patients with secondary hyperparathyroidism

R de Alarcon, B Alburquerque-Gonzalez… - Nephrology Dialysis …, 2022 - academic.oup.com
… The discovery of calcium-sensing receptor (CaSR) facilitated … of genetics in cinacalcet
inter-individual response and the … each rs4588 genotype before and after cinacalcet treatment, …

… -SENSING RECEPTOR GENE (CASR RS7652589) WITH NEPHROLITHIASIS AND SECONDARY HYPERPARATHYROIDISM IN HEMODIALYSIS PATIENTS

A Grzegorzewska, M Paciorkowski, A Mostowska… - 2016 - academic.oup.com
… Allosteric activators of the calcium-sensing receptor (CaSR) provide an … genotype is
associated with more severe sHPT, but PTH-decreasing response to treatment with cinacalcet

[HTML][HTML] Antilipolytic effect of calcimimetics depends on the allelic variant of calcium-sensing receptor gene polymorphism rs1042636 (Arg990Gly)

M Reyes, HM Rothe, P Mattar, WB Shapiro… - European journal of …, 2012 - nature.com
… of an antilipolytic response to cinacalcet could be explained by the genotype of rs1042636.
… -lowering dose–response to the calcimimetic cinacalcet in patients on hemodialysis. Recent …